Research Training Group 2498

Research Training Group 2498

Communication and Dynamics of Plant Cell Compartments

“Build and destroy: roles for targeted protein degradation in plant development and stress response”

Halle Plant Science Colloquium

presented by Daniel J. Gibbs (University of Birmingham, UK, Plant Proteolyis and Signalling)

Date: 23 February, 2021
Time: 3:30 pm to 5:00 pm
Location: Online (Webex), ID 121 934 8397, PW: fjXk3FhT7R7
Web-link: https://uni-halle.webex.com/uni-halle/j.php?MT…


Abstract: Proteins are essential functional components of cells, and as such their abundance and activity needs to be tightly controlled through their balanced production, modification and destruction.  In eukaryotic organisms, a predominant mechanism for regulated protein degradation (proteolysis) is through the ubiquitin proteasome system (UPS). Here, proteins are marked for turnover by so called E3 ubiquitin ligases that catalyse the addition of ubiquitin molecules to the target protein.  Compared to other kingdoms, the number of components linked to the UPS has significantly expanded in plant genomes, highlighting the enhanced importance of this cellular system in the plant lineage.  Here I will present published and on-going collaborative work in this area, with a particular focus on how plants use protein degradation as a mechanism for coordinating cellular processes and sensing and responding to environmental signals and stresses.  In particular I will highlight the importance of the ‘N-degron’ pathway of proteolysis for controlling flooding and low-oxygen-stress responses through functionally distinct transcriptional and epigenetic regulators.


The Halle Plant Science Colloquium (HPSC) is an interdepartmental colloquium of Institutions of the Martin-Luther-University working on any aspect of functional plant biology.

Interested in plant science? – Find more HPSC events listed here: https://www.landw.uni-halle.de/prof/pflanzenernaehrung/hpsc/


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